Preheat your oven to 475°F and line a sheet pan with parchment paper. While the oven heats, cut the salmon fillets into 1-inch bite-sized pieces and place them in a medium bowl. This upfront prep ensures your salmon is ready to marinate and cook as soon as your glaze is mixed, avoiding any delays in the cooking process.
In a separate bowl, whisk together the rice vinegar, soy sauce, red miso paste, honey, sesame oil, ground ginger, and garlic powder. Stir until the miso paste is completely dissolved and the mixture is smooth and well combined. I like to let the glaze sit for a minute after mixing to let the flavors start to meld together—it makes a noticeable difference in depth. The miso and soy sauce provide the umami backbone while the honey adds a subtle sweetness that balances the savory elements.
Pour the miso glaze from Step 2 over the salmon pieces in the bowl and gently toss until all pieces are evenly coated. Transfer the coated salmon to the prepared sheet pan, arranging the pieces in a single layer. Brush any remaining glaze from the bottom of the bowl over the top of the salmon pieces. I always save a bit of extra glaze to brush on top because it caramelizes beautifully during the high-heat bake and creates a gorgeous, glossy coating.
Place the sheet pan in the preheated 475°F oven and bake for 5-6 minutes, until the salmon is opaque throughout and the glaze is caramelized and sticky on top. The high heat will cook the delicate salmon quickly while allowing the miso glaze to develop a slightly charred, flavorful exterior. Check at 5 minutes—the salmon is done when it flakes easily with a fork and no longer appears translucent.
Remove the salmon bites from the oven and serve immediately while they're hot and the glaze is still glossy. These are best enjoyed fresh from the oven when the contrast between the caramelized exterior and tender interior is most pronounced.